MeniCare Pure (250ml) contact lens solution with case
Product description / Instructions for use
Natural composition
Natural polymer
ε-PL is a natural homopolymer of the essential amino acid L-lysine.
Naturally secreted by various Streptomycetaceae bacteria and some filamentous fungi. Industrial production of ε-PL is carried out by aerobic fermentation of the strain Streptomyces albulus.
Toxicity
Since ε-polylysine is a natural homopolymer of the essential amino acid L-lysine, the toxicity is lower than that of cationic disinfectants used in commercially available multi-purpose solutions.
Antimicrobial effect
Aε-PL shows high and broad antibacterial activity due to its cationic nature. The predominant mechanism of ε-PL antimicrobial activity is that it leads to electrostatic adsorption onto the cell surface of microorganisms, which leads to destruction of the outer membrane and abnormal distribution of cytoplasm.
Stability
After boiling at 100°C for 30 minutes or autoclaving at 120°C for 20 minutes or storage at room temperature for 3 years, no degradation/denaturation is observed.
Efficacy of MPS against biofilm
Inoculate staphylococcus epidermidis (isolated from contact lens users) with the culture medium (as a food source) and incubate the mixture for long enough to form a biofilm in the lens case.
Replace the culture medium on the MPS and allow them to soak for 4 hours.
The biofilm has destroyed almost all bacteria with the MENICARE PURE solution.
Cleaning
Artificial lipid (triglyceride) plates with 1% orange dye. * Triglyceride is one of the major lipids in tears
Measure the absorbance of the test solution after 1, 2, 4 and 8 hours to determine the amount of lipid solubilized by surfactant.
Protein denaturation
[Lysozyme]
Denatured protein can cause:
Hydrophobicity
Discomfort and allergies
Naturally derived surfactant prevents protein denaturation.
Methodology
Lysozyme was dissolved in each solution tube (final concentration 0.15%) and heated at 70°-90°C for 5 min. The denatured lysozyme becomes visible as whitish deposits.
Safety[Cytotoxicity test according to ISO 10993-5 (colony forming assay)] l'IC50 measurement
Double filtration: This method eliminates microorganisms and insoluble particles of any size.
User Guide
Opening the product
- The drip tray is closed.
- To open, unscrew the cap clockwise.
- The spike inside the cap will break through the seal.
Steps for use
Wash your hands thoroughly before handling the contact lenses:
Rub the lens gently with a few drops of MENICARE PURE for 20 seconds.
Place the lenses in the lens holder on the right and left and rinse them with MENICARE PURE.
Fill the lens case with MENICARE PURE and soak the lenses for at least 30 minutes or overnight.
Insert the lenses using MENICARE PURE.
After use, keep your lenses clean and dry.
You can store the lenses in an open case until they are ready to use, up to 30 days. If you store the lenses for longer periods, they should be cleaned and disinfected with MENICARE PURE solution every 30 days.
Menicon recommends the use of Progent SP-Intensivreiniger (2x5 pcs) intensive cleaner once a week.
Product benefits
Safe and convenient packaging for improved sterility and integrity
Easy-to-use bottle
Single-button cap.
The integrity of the container is maintained, opening and closing is automatic in one step.
The cap remains attached to the bottle, limiting the risk of contamination.
Manufacturer: Menicon Co., Ltd.
